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Methandriol Dipropionate

Jan 19

2 min read

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Methandriol Dipropionate (MDP) is a synthetic anabolic-androgenic steroid (AAS) derived from testosterone. It is a modified form of methandriol (17α-methyl-5-androstenediol) with dipropionate ester chains attached, which make it more lipophilic and extend its half-life when administered via injection.


Key Features:


1. Anabolic and Androgenic Properties:

Methandriol dipropionate has both anabolic (muscle-building) and androgenic (masculinizing) effects. However, its anabolic properties are generally considered to be moderate compared to other AAS.



2. Estrogenic Activity:

It has some estrogenic activity because it can aromatize into estrogen, which may lead to side effects such as water retention, gynecomastia, and fat gain if not controlled.



3. Administration:

Typically administered intramuscularly due to its esterified form, allowing for slower release and longer activity in the body.



4. Half-Life:

The dipropionate esters provide a moderate release profile, with an active duration of around 3–5 days.



5. Applications:

Methandriol and its derivatives have been used in medicine for treating conditions like delayed puberty, muscle wasting, and osteoporosis. However, its medical use is now rare due to better alternatives and concerns over side effects.




Common Uses in Sports:


Despite being banned by most sporting organizations, methandriol dipropionate has been used illicitly by bodybuilders and athletes to:


Enhance muscle mass and strength.


Promote recovery from intense training sessions.


Increase aggression and energy levels.



Potential Side Effects:


1. Androgenic Side Effects:


Acne


Increased body hair


Male pattern baldness


Virilization in women




2. Estrogenic Side Effects:


Water retention


Gynecomastia


Fat accumulation




3. Cardiovascular Issues:


Elevated cholesterol levels


Increased risk of hypertension




4. Hepatotoxicity:

Methandriol dipropionate is mildly hepatotoxic due to its 17α-methylated structure.



5. Suppression of Natural Testosterone:

Like other AAS, it suppresses endogenous testosterone production, necessitating post-cycle therapy (PCT).




Legal Status:


Methandriol dipropionate is classified as a controlled substance in many countries, and its non-medical use is illegal. It is also banned by organizations such as the World Anti-Doping Agency (WADA). 1nordicpharma.ca



Jan 19

2 min read

0

6

0

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